Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder displaying features reminiscent of premature senescence caused by germline mutations in the LMNA gene encoding lamin A and C. essential components of the nuclear lamina. By studying a family with homozygous LMNA mutation (K542N). we showed that HGPS can also be caused by mutations affecting both isoforms. https://www.pomyslnaszycie.com/halloween-skull-bride-groom-cheap/