Abstract Purpose We review key design elements of positive randomized controlled trials (RCTs) in acute ischemic stroke (AIS) treatment and summarize their main characteristics. Method We searched Medline. Pubmed and Cochrane databases for positive RCTs in AIS treatment. Trials were included if (1) they had a randomized controlled design. https://www.duospiritalis.com/limited-deal-Radio-Birdman-Rock-Roll-Soldiers-T-Shirt-super-grab/