Barren plateau landscapes correspond to gradients that vanish exponentially in the number of qubits. Such landscapes have been demonstrated for variational quantum algorithms and quantum neural networks with either deep circuits or global cost functions. For obvious reasons. it is expected that gradient-based optimizers will be significantly affected by barren plateaus. https://www.bekindtopets.com/super-pick-Rx-Quadruple-Topical-Ointment-Quadritrop-for-Dogs-Cats-30-mL-super-grab/