There exists a release of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to minimize afferent suffering transmission and generate analgesia. For that reason, medication like clonidine that concentrate on alpha-two receptors can affect the transmission of soreness. Clonidine is distributed in https://heinzv825udj1.wikienlightenment.com/user