In this particular manuscript, we describe nitrile-oxide electrophiles as helpful substitutes for chloroacetamide groups inside GPX4 inhibitors. Masked nitrile oxides exhibit amazing selectivity for GPX4 and diminished off-target consequences compared to chloroacetamide-dependent GPX4 inhibitors. This selectivity is unexpected on condition that nitrile oxides are considered The most r... https://juliad814qwb4.theobloggers.com/profile